Table 4: Talin-1 gene expression and AFP among the studied groups.
| Parameters |
Group I HCC
(N=40)
|
Group II Cirrhosis (N=30) |
Group III Control (N=30) |
P value |
|
Talin-1 Gene (2-∆∆CT) Mean± SD |
13.4 ±2.7 |
9.2 ±5.4 |
5 ±2.57 |
P1=0.000*
P2=0.000*
P3=0.000* |
|
AFP (ng/mL)Median (Range) |
37.47 (2.5-1000) |
10.55 (5.6 -51) |
5.69 (2.9-9) |
P1=0.67
P2=0.004*
P3=0.013* |
Data are presented as mean ± standard deviation or median with minimum and maximum values, as appropriate. HCC: Hepatocellular carcinoma;AFP: Alpha-fetoprotein;2-∆∆CT=relative gene quantification (CT=cycle threshold);*:Values statistically significant (at P< 0.05). P1: HCC vsCirrhotic; P2: HCC vsControl; P3: Cirrhotic vs Control.