Table 4: Diagnostic performance of serum AFP and serum fucosylated haptoglobin with combination of serum AFP at different cut-offs in HCC group versus cirrhotic and control group.

AFP
Cut-off Sensitivity Specificity PPV NPV
35 65% 95% 87% 84%
97 55% 98% 92% 81%
200 41% 100% 100% 75%
FucHapt
Cut-off Sensitivity
(95% CI) 		Specificity PPV NPV
116 80%
(56.3 - 94.3)		 65%
(48.3 - 79.4)		 53% 87%
AFP + FucHapt
AFP FucHapt Sensitivity Spec PPV NPV
35 116 95% 63% 56% 96%
97 116 95% 65% 58% 96%
200 116 95% 65% 58% 96%

PPV: positive predictive value, NPV: negative predictive value, AFP: Alfa fetoprotein, FucHapt: Fucosylated haptoglobin