Table 2: LD50 values of NDF* through different routes.
Route |
LD50 |
Oral |
>5 g/kg |
Dermal |
>5 g/kg |
Intraperitoneal |
>570 mg/kg |
Intratracheal |
>100 mg/kg |
Intranasal |
>100 mg/kg |
Primary skin irritation index (PSII) |
0.5 |
* NDF was suspended in 0.25% methyl cellulose for oral and was suspended in phosphate buffer for intratracheal, intranasal and intraperitoneal.