Table 3: Organ body weight index (%) of animals exposed with NDF by different routes and compared with their respective controls.

Routes Groups Doses Organs
Liver Lungs Spleen Heart Kidneys
Dermal
(14 days)		 Control - 3.37±0.31 0.71±0.02 0.3±0.06 0.38±0.01 0.69±0.04
Treated 5 g/kg 3.32±0.03 0.69±0.05 0.34±0.01 0.3±0.02 0.62±0.03
P value 0.878 0.723 0.535 0.3±0.02 0.211
Intratracheal Control - 3.56±0.15 1.00±0.01 0.47±0.04 0.31±0.00 0.62±0.03
Treated 100mg/kg 3.29±0.22 1.10±0.12 0.26±0.02 0.3±0.01 0.6±0.03
P value 0.368 0.453 0.009* 0.374 0.662
Intranasal Control - 4.89±0.27 1.29±0.04 0.68±0.09 0.44±0.02 1.01±0.02
Treated 100mg/kg 5.05±0.37 1.53±0.12 0.48±0.05 0.48±0.05 1.09±0.06
P value 0.739 0.107 0.100 0.486 0.253
Intraperitoneal Control - 5.58±0.17 1.07±0.02 0.65±0.06 0.43±0.03 0.93±0.04
Treated 570mg/kg 6.26±0.25 0.95±0.12 0.52±0.04 0.49±0.01 1.05±0.03
P value 0.066 0.362 0.121 0.107 0.053
Oral Control - 2.963
±0.205		 0.758
±0.031		 0.382
±0.038		 0.414
±0.033		 0.625
±0.036
Treated 500g/kg 3.174
±0.039		 0.765
±0.055		 0.328
±0.033		 0.311
±0.006		 0.581
±0.018
P value 0.232 0.928 0.345 0.007* 0.266
Inhalation NF 40 g 3.103
±0.153		 0.825
±0.018		 0.404
±0.052		 0.372
±0.005		 0.588
±0.032
P value 0.965 0.267 0.698 0.029* 0.0533

Values represented in mean ± SE, n=4. P < 0.05 (Student’s t-test), as compared to control group. * significant value.