Table 4: Changes in the biochemical parameters in plasma samples of animals exposed with NDF through oral, dermal, interperitonial, intratracheal and intranasal routes and compared with their respective controls.

Biochemical Parameters Oral
(5 g/kg)
Dermal
(2 g/kg)
Intra-peritonial
(570 mg/kg)
Intratracheal
(100 mg/kg)
Intranasal
(100 mg/kg)
%AST 74.4±7.5 96.4±6.3 137.8±57.4 193.7±40 180.6±47.1
%ALT 69.9±7.5 95.2±5.2 100.9±23.4 94.9±6.1 157.8±12.7
%ALP 100 ± 12.3 99.9±24.5 99.9±27.2 161.1±17.3 49.7±8.3
%LDH 161.7±78.2 119.1±119.1 113.6±13.6 332.8±100 139.9±12.0
%BUN 118.3±16.9 93.1±6.1 131.5±44.4 115.6±17.6 100.7±21.7
%CR - 93.5±9.7 95±5 100±0 58.3±11.0
%Glucose 98.6±9.7 119.6±8.3 113.2±11.9 128.8±17.9 90.6±2.03
%Protein 114.8±7.0 105.4±2.0 98.4±5.9 99.8±0.7 101.4±7.1
%Triglycerides 98.8±27.4 111.9±24.8 170.8±87.0 118.4±118.4 117.3±15.5
%Cholesterol 115.9±17.2 88.7±6.8 104.1±106.5 114.6±15.5 85.5±4.2

AST (Aspartate aminotransferase), ALT (Alanine aminotransferase), LDH (Lactate dehydrogenase), BUN (Blood urea nitrogen), CR (Creatinine). Values represented in mean ± SE, n=4. P < 0.05 (Student’s t-test), * significance as compared to respective control group.