Table 3: Coefficients of model parameters and p- statistics obtained from the fitted model.

	Model factors	Coefficients	P-value
	Constant	7.00	<0.0001
CBY	A	0.37	<0.0001
	B	-0.049	0.0276
	C	-0.091	0.0008
	A2	-0.28	<0.0001
	B2	-0.15	<0.0001
	C2	-0.065	0.0054
	AB	-0.037	0.1618
	AC	-0.087	0.0055
	BC	-0.14	0.0002
	R2	0.9929
	Constant	69.90	<0.0001
	A	3.78	<0.0001
BC	B	-0.75	0.0007
	C	-0.76	0.0007
	A2	-2.77	<0.0001
	B2	-1.36	<0.0001
	C2	-0.72	0.0008
	AB	-0.64	0.0109
	AC	-0.71	0.0061
	BC	-1.38	<0.0001
	R2	0.9908
	Constant	9.00	<0.0001
HRT	A	-0.96	<0.0001
	B	0.39	<0.0001
	C	0.81	<0.0001
	A2	1.26	<0.0001
	B2	0.37	0.0001
	C2	8.813E-03	0.0249
	AB	-0.16	0.0114
	AC	0.25	0.0114
	BC	0.50	0.0001
	R2	0.9900