Table 3: Regression analysis of CCD showing model coefficients and significance of regression coefficient for ChOx activity.

Term	Coef	SE Coef	T-Value	P-Value
Constant	4.0617	0.0677	60.01	0.000
X1	0.0395	0.0309	1.28	0.211
X2	-0.2577	0.0309	-8.34	0.000
X3	-0.1942	0.0309	-6.28	0.000
X4	0.2176	0.0309	7.04	0.000
X5	-0.2109	0.0309	-6.82	0.000
X6	-0.1549	0.0309	-5.01	0.000
X12	-0.4134	0.0264	-15.66	0.000
X22	-0.2114	0.0264	-8.01	0.000
X32	-0.0904	0.0264	-3.42	0.002
X42	-0.3152	0.0264	-11.94	0.000
X52	-0.4101	0.0264	-15.54	0.000
X62	-0.0999	0.0264	-3.79	0.001
X1*X3	-0.1329	0.0360	-3.70	0.001
X1*X4	0.0501	0.0360	1.39	0.174
X1*X5	0.0795	0.0360	2.21	0.035
X1*X6	0.2107	0.0360	5.86	0.000
X2*X4	-0.1017	0.0360	-2.83	0.008
X2*X5	0.2840	0.0360	7.90	0.000
X3*X4	-0.1268	0.0360	-3.53	0.001
X3*X5	-0.1149	0.0360	-3.20	0.003
X3*X6	-0.0399	0.0360	-1.11	0.276
X4*X5	-0.0729	0.0360	-2.03	0.052
X5*X6	-0.0673	0.0360	-1.87	0.071
S = 0.2034, R-sq = 97.09%, R-sq (adj) = 94.79 %, R-sq (pred) = 87.22 %