| Outcome | Cut off for Age of Study population | Study Design | Participants in Premature/late Onset Group, n | Source |
|---|---|---|---|---|
| Cardiovascular disease | 30-60 years vs ≥60 years | cohort | 275 /237 | Hadaegh, 2013 (14) |
| Myocardial Infarction | ≤ 50 vs >50 | Cross sectional | 151/429 | Mahmoodi, 2007 (9) |
| CAD patients underwent CABG | <45 vs >65 | Cross sectional | 277/423 | Safaei, 2011 (10) |
| Acute ST-segment elevation myocardial infarction | ≤35 vs >35 | Cross sectional | 108 /5544 | Hosseini, 2011 (8) |
| Angiographic documented CAD | <55 vs ≥55 | case control | 103 / 110 | Vaisi-Raygani, 2010 (12) |
| Myocardial Infarction | (Women ≤55 Men ≤50) vs (Women >55 men >50 |
cohort | 200/623 | Sadrebafeghi, 2005 (13) |
| CAD (ICD-10): I20-I25 | ≤45 vs >45 | Cross sectional | 200 /400 | Soleimani, 2010 (11) |