Table 3: Risk factor definition in papers included in meta-analysis.

Risk Factor Definitions in Papers
Diabetes 1- Mahmoodi (2007): Diabetes mellitus was defined as fasting blood glucose levels >125 mg/dL or a history of diabetes in the past or present with or without medication use at the time of admission
2- Hadaegh (2013): Diabetes mellitus was defined as fasting plasma glucose (FPG) level ≥7 mmol/L and the current use of anti-diabetic drugs
3- Hosseini (2011): symptoms of diabetes and plasma glucose
concentration ≥ 200 mg/dl (11.1 mmol/l), or fasting blood
sugar (FBS) ≥ 126 mg/dl (7.0 mmol/l) or after 2-h ≥ 200 mg/dl
(11.1 mmol/l)
4- Safaei (2011): Not defined in the paper
Hyperlipidaemia 1- Mahmoodi (2007): Hyperlipidaemia was defined as documented history with or without use of antilipidaemic drugs or having cholesterol levels >200 mg/dL or triglyceride level >150 mg/dL or both
2- Sadrebafeghi (2005): Hyperlipidaemia was defined as history of antilipidaemic drugs or cholesterol levels >200 mg/dL or triglyceride level >150 mg/dL or LDL>160
5- Safaei (2011): Not defined in the paper
Hypertension 1- Mahmoodi (2007): Hypertension was defined as a history of HTN in the past or blood pressure ≥140/90 mmHg with or without antihypertensive medication at the time of admission
2- Safaei (2011): SBP of 140 mmHg or higher DBP of 90 mmHg or higher or current use of antihypertensive medication
3- Sadrebafeghi (2005): documented history of hypertension or antihypertensive drug
4- Hosseini (2011): systolic blood pressure ≥140 and/or diastolic ≥90 mmHg and/or on anti-hypertensive treatment
5- Vaisi-Raygani (2010): Hypertension was defined as resting systolic blood pressure ≥160 mmHg and diastolic blood pressure ≥95 mmHg or used anti hypertension drugs.
6- Soleimani (2010): Not defined in the paper
Smoking 1- Hadaegh (2013): Smoking status was defined on the basis of response to the smoking behaviour questions: those who have never smoked, former smokers and current smokers.
2- Mahmoodi (2007): Smoking habit was ascertained by questionnaire and defined as current smoker and never smoked
3- Hosseini (2011): patient regularly smokes a tobacco product/products one or more times per day or has smoked in the 30 days prior to admission
4- Sadrebafeghi (2005): History of smoking >10 cigarettes/day in 3 months
5- Safaei (2011): Not defined in the paper
6- Soleimani (2010): Not defined in the paper
Family history of CAD 1- Hadaegh (2013): Family history of premature CVD reflected any prior diagnosis of CVD in female first-degree relatives, aged less than 65 years or male first-degree relatives under the age of 55 years old.
2- Mahmoodi (2007): Family history was defined as MI history in one parent or both.
3- Hosseini (2011): first degree relatives before the age of 55 years in men and 65 years in women
4- Safaei (2011): Not defined
5- Soleimani (2010): Not defined

CVD: Cardiovascular Disease, DBP: Diastolic Blood Pressure, LDL: Low Density Lipoprotein, MI: Myocardial Infarction, SBP: Systolic Blood Pressure.