Changes in blood pressure are presented as the weighted least-squares mean changes ± SEM (not all variability information was provided in the trial of Villamil (2007) [
21], preventing the use of an approximation for SEM or confidence intervals estimation for the first three aliskiren/HCTZ dose combinations).
a The range presented is due to the trial of Villamil (2007) [
21], which presented the range of BP control rate for aliskiren/HCTZ combination, without specify the values for each dose combination.
BP – Blood pressure; DBP – Diastolic blood pressure; HCTZ – Hydrochlorothiazide; SBP – Systolic blood pressure.