Long-Term Follow-Up of Cognitive Function and Activities of Daily Living in Older People: A Feasibility Study in the PROSPER Cohort

Table 2: Baseline Characteristics of PROSPER Survivors who have Developed Dementia or Significant Cognitive Impairment Compared to Survivors who have Not

Baseline Characteristic	Alive No Dementia (n=63)	Alive with Dementia (n=28)	p
Age (years), mean (SD)	74.0 (3.0)	76.0 (3.6)	0.007
Gender (male)	29 (46.0%)	11 (39.3%)	0.55
History of Vascular Disease	30 (47.6%)	16 (57.1%)	0.40
Diabetes	4 (3.2%)	2 (7.1%)	1.00
Current Smoker	8 (12.7%)	5 (17.9%)	0.35
Any alcohol intake	35 (55.6%)	12 (42.9%)	0.26
Randomised to Pravastatin	30 (47.6%)	14 (50.0%)	0.83
Education (years), mean (SD)	15.1 (1.4)	14.8 (1.2)	0.44
^SBP (mmHg), mean (SD)	148.7 (20.6)	157.2 (24.7)	0.094
^CRP (geometric mean), (SD)	2.6 (3.4)	2.1 (3.9)	0.50
^IL6 (geometric mean), (SD)	2.1 (1.9)	2.0 (1.7)	0.73
^D-dimer (geometric mean), (SD)	228.8 (1.6)	260.4 (1.7)	0.23

SBP = systolic blood pressure.

CRP = C-reactive protein.

IL6 = Interleukin-6.

D-dimer = a fibrin degradation protein tested in the blood to help diagnose thrombosis.

Results of continuous variables are mean (SD) except where stated; categorical variables are summarised as number (%). Continuous variables are analysed by 2 sample t-test (using log-transformed data for IL-6 and CRP), and categorical data by Chi-squared or Fisher’s exact test as appropriate.