Table 3: Overall differences overtime.

Model Baseline
(T1) 		T2 End of the treatment
(T3) 		p value
In vivo
(Ncm) 		15.81 ± 5.61 9.65 ± 4.15 11.92 ± 5.84 0.031 (T3 vs T2)
<0.001 (T3 vs T1)
<0.001 (T2 vs T1)
In vitro
(Ncm) 		12.50 (18.75 - 10.00) 8.00 (11.50 - 5.00) <0.001