Fig. (3) 3D visualization of the performance frontier according to titratable acidity, viscosity and sucrose concentration. Grey area corresponds to the frontier where medicines with 100% performance are included. Klaricid® 50 mg/5mL and Zinnat® 250 mg/5mL were distant from the performance frontier, which means that these medicines have the worst performance and, therefore, greater potential for dissolution of dental enamel.