Table 1: Literature analysis of articles focused on AG related to nutritional deficiency.

Year Author Methods Results Reference
1993 Drinka et al. Nutritional status of 20 elderly patients with a normal tongue and 10 subjects with various degree of AG Their results demonstrated a statistically significant association between AG and deficiency of vitamin E, considered as another nutrient responsible for the development of AG. [16]
2000 Bøhmer and Mowe Nutritional status of 416 old people and the resulting lingual alterations. The correlation between AG and nutritional indices was statistically significant, and related to low levels of haemoglobin, cholesterol, ascorbic acid, serum iron and serum cobalamin. [17]
2012 Sun et al. Comparison of blood hemoglobin concentration, iron, cobalamin, folic acid and homocysteine in 176 patient with AG with 176 healthy controls Their results showed a statistically significant association among AG and low serum concentration of iron, vitamin B12 and haemoglobin. Patients with AG showed high homocysteine levels. [18]
2013 Sun et al. Evaluation of the reduction of homocysteine levels in 91 patients with an AG AG healed through supplementation of different vitamins and iron [19]
2014 Wu et al. Comparison of prevalence of AG studying nutritional status of 75 patient with iron-deficiency anemia and of 150 healthy subjects. Serum concentration of iron, vitamin B12, folic acid and homocysteine was quantified in the blood samples of all cases. Results showed statistically significant differences in the iron and cobalamin concentrations between the two study groups, while no differences were identified for the other two nutrients [9]
2014 Demir N et al. Analysis of prevalence of AG in 57 neonatal patients with vitamin B12 deficiency Determination of a prevalence of AG of 70.17%. The authors concluded that a deficiency of vitamin B12 should be considered in the differential diagnosis of infants who present with skin and mucosal lesions. [124]
2016 Bao ZX et al. Analysis of serum zinc levels in 368 patients (of which 54 had an AG). The mean serum zinc level in the healthy control group was significantly higher than that of the AG group. [31]

Back to Article