November 1996 |
Diagnosis of monocytic AML (age 5), by the Department of Pediatric Oncohematology of Policlinico San Matteo of Pavia; |
- |
Chemotherapy for the diagnosed AML, according to the modified AIEOP LAM 92 protocol; |
March 1997 |
Diagnosis of medullary recidivism (age 6) refractory to the above chemotherapy protocol upon its re-introduction; |
April 1997 |
Allogenic bone marrow transplantation from an HLA-adequate donor (the patient’s brother), after conditioning via busulfan, cyclophosphamide, and melphalan administration; |
April 1998 |
Diagnosis of new recidivism at the rear-peritoneal abdominal level (age 7); |
July 1999 |
Allogenic bone marrow transplantation from patient’s brother, after a myeloablative treatment via total-body irradiation combined with cyclophosphamide and thiotepa; |
January 2009 |
Diagnosis of AML-free (age 18) after reaching the 10-year disease-free checkpoint. |