Table 3: Detailed quality information of studies included in the review.

Authors/
Year
Study Design Sample Description Total Dtudy Time/Interval Times Periodontal Index Statistical Analysis Conclusion
Ristic M / 2007 Prospective longitudinal controlled study 32 subjects,
13 males and 19 female
(from 12 to 18 years old)
before placement of fixed appliance
1, 3, 6 months after
PI, GI, PPD, GBI Student’s t-test and chi-squared test combined with McNemar test In adolescents, treatment increased the value of periodontal indices.
Liu H / 2011 Not mentioned Group A (at the beginning of treatment)
28 subjects, 22 females, 6 males (17.6+- 5.68 y)
Group B (at the completation of treatment)
20 subjects
13 female, 7 males
(17.8± 4.49 y)
Group A
Before placement of appliance and 1, 3 months after
Group B
Before appliance removal and 1, 3,6 month after appliance removal
PI, GI, PPD SPPS 16.0 for statistical analysis,
T-test and Spearman test
Fixed orthodontic treatment is conducive to dental plaque accumulation and gingival infiammation. After removal of orthodontic appliances the periodontal condition improved.
Van Gastel J / 2008 Longitudinal split-mouth desisgn 24 subjects, 10 boys and 14 girls
(14.6± 1.1 years)
Before placement appliance and 20, 24, and 36 weeks after PPD, BOP A linear mixed model was used with the data, using time, type, and their interaction as fixed factors.. Multiple comparisons between types and times were set up and a comparison of times was also performed for two types of subgroups. Placement of both types of orthodontic attachments had a negative influence on the microflora and the clinical periodontal variables
Ghijselings E / 2014 Longitudinal prospective design 24 subjects, 10 males, 14 females (14.6±1.1 y) Before placement of appliance, after bracket removal and 2 years post-treatment PPD and BOP A linear mixed model was used with the data, using time, type, and their interaction as fixed factors.. Multiple comparisons between types and times were set up and a comparison of times was also performed for two types of subgroups Normalization toward the values at baseline was seen 2 years after removal of appliances
Van Gastel J/
2011
Longitudinal prospective design 24 subjects, 10 males, 14 females (14.6±1.1 y) Before placement of appliance (T1), after bracket removal (T2) and 3 months post-treatment (T3). PPD and POB A linear mixed model was used with the data, using time, type, and their interaction as fixed factors.. Multiple comparisons between types and times were set up and a comparison of times was also performed for two types of subgroups Clinical parameters PPD, POB, and GCF flow showed a significant increase between T1 and T2. Between T2 and T3 these variables decreased significantly but remained significantly higher than at T1 (except for BOP values at the bonded sites)