Table 1: Previous articles about peripheral calcifying epithelial odontogenic tumor including clear cell variant with emphasis in the treatment.

Authors Anatomic Site Duration Clinical Presentation Imaging
Presentation
Treatment Recurrence Folow-up
Pindborg, 19665 Max.
gingiva
5 years Painless firm
mass
NCI Simple excision No NCI
Abrams and Howell, 196710** Mand. gingiva NA Painless firm
mass
Crest
resorption
Simple excision No 3 years
Decker and Laffitte, 196711 Mand.
gingiva
5years Painless firm
mass
NCI Simple excision No NCI
Patterson et al, 196912 Mand. gingiva 1 year Painless firm
mass
NCI Simple excision No NCI
Krolls and Pindborg, 197413 Mand. gingiva NA Painless firm
mass
NCI Simple excision No NCI
Wherteimer et al., 197714** Max. gingiva NA Painless firm
mass
No Simple excision No NA
Ai-ru et al., 198215** Mand. gingiva 10 years Painless firm
mass
NCI Ressection No 2 years
Ai-ru et al., 198215** Mand. gingiva 2 years Painless firm
mass
No Partial
ressection
No 10 years
Takeda et al., 198316 Max
gingiva
NA Painless firm
mass
NCI Excision underlying bone No NCI
KH Ng et al., 199617 Max.
gingiva
1 year Painless firm
swelling
Erosion Excision No NA
Houston & Fowler, 199718** Max.
gingiva
5 months Ulcerated
mass
No Simple excision No 4 years
Houston & Fowler, 199718** Mand.
gingiva
5 months Ulcerated
mass
Erosion* Simple excision No 4 years
Orsini et al., 20009** Max. gingiva 6 months Painless red
mass
Not
performed
Simple
excision
No 4 years
Mesquita et al., 20036** Max. gingiva 10 months Painless firm
nodule
No Excision No 2.5 years
de Oliveira et al., 20092** Max. gingiva NA Painless exophitic mass No Excision No 1 year
de Oliveira et al., 20092** Mand. gingiva NA Painless exophitic mass Superficial cupping Excision No 1 year
Abrahão et al., 200919b Mand
gingiva
3 months Painfull erithematous swelling Noa Simple excisionc Yesd 3.5 years
Habibi et al., 200920** Max.
gingiva
11 years Ulcerated
mass
NCI Excisional biopsy with 5-mm safety margins No NA
Marino et al., 201321 Max. gingiva NA Painless
swelling
Bone
resorption
Conservative surgery including teeth extraction No 2 years
Afrogheh
et al., 20147**
Mand. gingiva 6 months Painless
swelling
Erosion Complete excision No 1.5 years
Shetty et al., 201622** Mand. gingiva 8 months Painless swelling No Excisional biopsy No 6 months
de Carvalho et al., 201626 Mand.
gingiva
1 month Painless swelling No Excisional
biopsy
No 1 year
Bajpai M,
201823**
Max.
gingiva
9 months Pink-coloured
swelling
Loss of lamina dura Complete
excision
No 6
months
Flores et al., 2018**¡ Mand. gingiva 4 years Painless
swelling
Superficial
hypodense
cupping
Conservative surgery No 22 months

Max.= maxillary Mand. = mandible NA = Not available NCI = Not clearly identified a = osseous resorption and calcifications (recurrent lesions) b = bilateral c = soft tissue excision followed bone curettage d = after 1 year *Observed only during the surgical procedure **Clear cell variant ¡ Current case

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