Table 3: Summary of finding table and quality of evidence (GRADE) assessment.

Certainty Assessment № of Patients Effect Certainty Importance
№ of Studies Study Design Risk of Bias Inconsistency Indirectness Imprecision Other Considerations PCOS Healthy Cohort Relative
(95% CI) 		Absolute
(95% CI)
Clinical Attachment Loss
4 observational studies not serious very serious a not serious not serious none 329 cases 285 controls RR 0.27
(0.19 to 0.36) 		- –
- 0.0% 0 fewer per 1,000
(from 0 fewer to 0 fewer)
Probing depth
2 observational studies not serious not serious not serious serious b none 111 cases 67 controls RR 0.35
(0.21 to 0.48) 		- –
- 0.0% 0 fewer per 1,000
(from 0 fewer to 0 fewer)
Gingiva Index
3 observational studies not serious very serious a not serious not serious none 231 cases 187 controls RR 0.70
(0.29 to 1.11) 		- –
- 0.0% 0 fewer per 1,000
(from 0 fewer to 0 fewer)
Bleeding on Probing (%)
2 observational studies not serious very serious a not serious serious b none 0 cases 0 controls RR 34.41
(20.23 to 48.59) 		- –
- 0.0% 0 fewer per 1,000
(from 0 fewer to 0 fewer)
Plaque index
3 observational studies not serious very serious a not serious serious b none 209 cases 165 controls RR 0.42
(-0.29 to 1.12) 		- –
- 0.0% 0 fewer per 1,000
(from 0 fewer to 0 fewer)

CI: Confidence interval; RR: Risk ratio
Explanations
a. Substantial heterogeneity
b. Total participants <400