Fig. (4) Bar graph presenting COL-I (a), MMP-1 (b), and SPARC (c) protein levels VH and CsA-treated gingival fibroblasts obtained from young and aging healthy donors, assessed by slot blot or Western blot analysis, as described in the Material and Methods section. Data are reported as densitometric units after scanning of the immunoreactive bands. Values are means ± SD for duplicate samples. VH: vehicle.