Table 2: Histopathological and Immunohistochemical Analysis of the Integrity of the Basement Membrane Based on the Expression of Type VII Collagen

Grade of Staining Intensities For Anchoring Fibrils Healthy Subjects (n=10) Patients with Upper Dentures (n=4) Patients with Class II Denture Stomatitis (n=8)
Grade 1: well defined borderline (++) 8 2 1
Grade 2: more marked borderline (+++) 2 0 4
Grade 3: patchy distribution or disruptions in the borderline (++/-) 0 0 2
Grade 4: discontinuities or disruptions in the borderline (+/-) 0 2 1

(a) Determined according to Thorup et al. [15,16]