Table 2: Characteristics of the Study Population in Terms of Severity of Periodontal Disease; Age and CRP level as mean ± SD; LE = Lifetime Exposure as Number of Cigarettes; NS = not Significant

Variable Normal Moderate PD Severe PD P
N 11 48 42 -
Age (years) 35.0 ± 9.6 37.2 ± 9.3 44.2 ± 9.2 0.001a)
Smoking:
Non-smoker
LE < 100000
LE 100000
7 (63.6%)
4 (36.4%)
0 (0%)
20 (41.7%)
23 (47.9%)
5 (10.4%)
12 (28.6%)
14 (33.3%)
16 (38.1%)
0.005
CRP (mg/L)
N with > 3 mg/L 		2.1 ± 3.9
1 (9.1%)		 2.0 ± 2.3
8 (17.0%)		 2.5 ± 3.9
8 (20.0%)		 0.743 NSa)
0.491 NS
IL-1B (3954):
CC
CT
TT
11 (100%)
0 (0%)
0 (0%)
46 (95.8%)
0 (0%)
2 (4.2%)
39 (92.9%)
3 (7.1%)
0 (0%)
0.587 NS
CRP (717):
SS
Ss
ss
10 (90.9%)
0 (0%)
1 (9.1%)
26 (54.2%)
18 (37.5%)
4 (8.3%)
25 (59.5%)
14 (33.3%)
3 (7.2%)
0.047
CRP (1444):
BB
Bb
bb
1 (9.1%)
10 (90.9%)
0 (0%)
3 (6.25%)
45 (93.75%)
0 (0%)		 2 (4.8%)
40 (95.2%)
0 (0%)
0.857 NS

a) Kruskal-Wallis test