Fig. (1) Box- and whiskerplot of the release (μg/ml) of TreVitaMix (TVM) and propylene glycol (PG) up to 21 days. Release in μg/ml at baseline (unfilled teeth) and after day 1, 3, 5, 7, 11, 14 and 21 are presented for TVM and PG. Asterisks indicate significant differences between TVM- and PG-group for each measurement, bars indicate significant differences within groups between different time points.