Combination of Root Surface Modification with BMP-2 and Collagen Hydrogel Scaffold Implantation for Periodontal Healing in Beagle Dogs

Table 1.: Histomorphometric analysis (means ± SD).

	Control group (n = 9)	BMP group (n = 9)	Col group (n = 8)	BMP/Col group (n = 8)
Defect height (mm)	4.73 ± 0.21	4.55 ± 0.24	4.91 ± 0.36	4.79 ± 0.40
Defect width (mm)	2.97 ± 0.17	3.04 ± 0.13	3.19 ± 0.17	3.07 ± 0.19
New cementum (mm)	0.34 ± 0.26	1.47 ± 0.61*	1.84 ± 0.79*	2.62 ± 0.70*†
New periodontal ligament (mm)	0.32 ± 0.25	0.86 ± 0.34	1.34 ± 0.62*	2.21 ± 0.77*†§
New bone height (mm)	0.81 ± 0.30	2.82 ± 0.69*	1.88 ± 0.56*	3.06 ± 1.08*§
New bone area (mm2)	1.64 ± 0.65	4.16 ± 0.85*	4.56 ± 1.07*	7.64 ± 3.12*†§
Ankylosis (mm)	0.00 ± 0.00	0.53 ± 0.83	0.03 ± 0.08	0.04 ± 0.11
Gingival connective tissue (mm)	2.91 ± 0.93	1.53 ± 0.50*	1.58 ± 1.04*	1.33 ± 0.69*
Junctional epithelium (mm)	0.94 ± 0.90	0.20 ± 0.30	1.04 ± 0.95	0.40 ± 0.50
Gingival recession (mm)	0.34 ± 0.49	0.02 ± 0.07	0.13 ± 0.35	0.00 ± 0.00

^* Statistical difference vs. control group (p < 0.05).

^† Statistical difference vs. BMP group (p < 0.05).

^§ Statistical difference vs. Col group (p < 0.05).