Table 3: Percentages of Compounds Falling into Good Prediction, Under Prediction and Over Prediction and r Values Using Model A, B, E and F (N=146)

Model	% of Compounds			r
	Good Prediction	Under Prediction	Over Prediction
Well-stirred model No binding (Model A) Including fu, plasma (Model B) Parallel-tube model No binding (Model E) Including fu, plasma (Model F)	44.52 13.9543.15 16.28	28.77 80.6224.66 76.74	26.71 5.4332.19 6.98	0.26 0.040.26 0.04