Table 4: Percentages of Compounds Falling into Good Prediction, Under Prediction and Over Prediction and r Values of 35 Compounds
Using 1 µM or 10 µM Substrate Concentrations in Metabolic Stability Study. Predicted CL was Calculated Based
on Model A
| Substrate Concentration (µM) |
% of Compounds |
r |
| Good Prediction |
Under Prediction |
Over Prediction |
1 µM
10 µM |
45.7
25.7 |
11.4
48.6 |
42.9
25.7 |
-0.03
-0.10 |