Table 8: Classification of 146 Compounds Based on In Vivo CL. Percentages of Compounds Falling into Good Prediction, Under Prediction and Over Prediction and r Values Using Model A

In Vivo Clearance % of Compounds r
Good Prediction Under Prediction Over Prediction
< 30 mL/min/kg (N = 97)
30-70 mL/min/kg (N = 30)
> 70 mL/min/kg (N = 19)		 53.7
30.8
23.8		 15.9
26.9
66.7		 47.6
-
-		 0.011
-0.039
-0.512