Time (hr) | 1.5 mg/kg Mean [+/-SD] N=24 | 3.0 mg/kg Mean [+/-SD] N=24 | 6.0 mg/kg Mean [+/-SD] N=24 | 12.0 mg/kg Mean [+/-SD] N=23 | |
---|---|---|---|---|---|
Infusion Period | 0a | 0
[0] |
0
[0] |
0
[0] |
0
[0] |
0.5a | 7761
[1130] |
17713
[3021] |
38838
[6162] |
77186
[11297] |
|
1a | 15280
[2783] |
34625
[5621] |
84083
[13648] |
154713
[26503] |
|
1.5a | 24052
[3653] |
52052
[9039] |
129204
[16063] |
254994
[40017] |
|
2a | 26284
[3918] |
63063
[16099] |
131549
[17324] |
313554
[41271] |
|
4 | 14419
[3384] |
52167
[7646] |
121122
[13000] |
325913
[51980] |
|
6 | 4633
[3518] |
36334
[6390] |
104426
[16384] |
264232
[40440] |
|
10 | 40
[56] |
12934
[7139] |
73627
[12514] |
21550
[28998] |
|
14 | 24
[12] |
1755
[3188] |
50440
[13547] |
195145
[32153] |
|
18 | 33
[19] |
61
[103] |
26522
[13128] |
153467
[22857] |
|
22 | 35
[7] |
23
[14] |
10769
[12496] |
146773
[27505] |
|
26 | 24
[16] |
19
[10] |
1839
[4367] |
94579
[31429] |
|
32 | 22
[17] |
7
[4] |
28
[55] |
54615
[29332] |
|
38 | 18
[10] |
23
[14] |
16
[11] |
21795
[21939] |
|
50 | 22
[14] |
29
[10] |
16
[11] |
419
[1373] |
|
74 | 31
[12] |
15
[10] |
22
[16] |
15
[7] |