Table 6: The Comparison of Epileptic Pregnant Women without Treatment (“No”), with Monotherapy (“Mono”) and Polytherapy (“Poly”) in the Control Group and in the Case Group Including Cases with Different CAs During the Two Study Periods: 1980-1989 and 1990-1996

Study Groups No. 1980 – 1989 No. 1990– 1996
No Mono Poly Total No Mono Poly Total
No. % No. % No. % No. % No. % No. % No. % No. %
Controls 25,349 7 0.03 23 0.09 22 0.09 52 0.21 12,803 3 0.02 27 0.21 8 0.06 38 0.30
Isolated CAs
Neural-tube defects 1,023 0 0.00 4 0.39 1 0.01 5 0.49 179 1 0.56 0 0.0 1 0.56 2 1.12
Cleft lip ± palate 873 0 0.00 1 0.11 7 0.80 8 0.92 502 0 0.00 1 0.20 2 0.40 3 0.60
Cleft palate 412 0 0.00 2 0.49 3 0.73 5 1.21 189 0 0.00 0 0.00 0 0.00 0 0.00
Cardiovascular CAs 2,664 2 0.08 5 0.19 10 0.38 17 0.64 1,816 3 0.17 3 0.17 2 0.11 8 0.44
Oesophageal atresia/stenosis 146 0 0.00 2 1.37 0 0.00 2 1.37 71 0 0.00 0 0.00 1 1.41 1 1.41
Hypospadias 1,846 1 0.05 2 0.11 2 0.11 5 0.27 1,192 2 0.17 5 0.42 1 0.08 8 0.67
Undescended testis 1,267 0 0.00 5 0.19 0 0.00 5 0.39 785 0 0.00 1 0.13 1 0.13 2 0.25
Clubfoot 1,614 0 0.00 3 0.19 1 0.06 4 0.25 811 0 0.00 1 0.06 0 0.00 1 0.14
Poly/syndactyly 1,042 2 0.19 0 0.00 1 0.10 3 0.29 702 0 0.00 1 0.14 1 0.14 2 0.28
Other isolated CAs 2,770 1 0.04 3 0.11 3 0.11 7 0.25 1,590 0 0.00 1 0.06 1 0.06 2 0.13
Multiple CAs 951 0 0.00 1 0.11 3 0.32 4 0.42 398 0 0.00 0 0.00 1 0.25 1 0.25
Total 14,608 6 0.04 28 0.19 31 0.21 65 0.44 8,235 6 0.07 13 0.16 11 0.13 30 0.36