Table 8: Use of Folic Acid (FA) During Pregnancy in the Different Study Groups According to Two Study Periods: 1980-1989 and 1990-1996
| Control Mothers |
| Period |
without epilepsy |
epileptic without AED |
epileptic with monotherapy |
epileptic with polytherapy |
all epileptics |
| No. |
% |
No. |
% |
No. |
% |
No. |
% |
No. |
% |
| 1980-1989 |
|
| FA |
13,364 |
52.8 |
2 |
28.6 |
11 |
47.8 |
8 |
36.4 |
21 |
40.4 |
| No FA |
11,933 |
47.2 |
5 |
71.4 |
12 |
19.2 |
14 |
63.6 |
31 |
59.6 |
| Subtotal |
25,297 |
100.0 |
7 |
100.0 |
23 |
100.0 |
22 |
100.0 |
52 |
100.0 |
| 1990-1996 |
|
| FA |
7,367 |
57.7 |
1 |
33.3 |
17 |
63.0 |
5 |
62.5 |
23 |
60.5 |
| No FA |
5,397 |
42.3 |
2 |
66.7 |
10 |
37.0 |
3 |
37.5 |
15 |
39.5 |
| Subtotal |
12,764 |
100.0 |
3 |
100.0 |
27 |
100.0 |
8 |
100.0 |
38 |
100.0 |
| 1980-1996 |
|
| FA |
20,731 |
54.4 |
3 |
30.0 |
28 |
56.0 |
13 |
43.3 |
44 |
48.9 |
| No FA |
17,330 |
45.6 |
7 |
70.0 |
22 |
44.0 |
17 |
56.7 |
46 |
51.1 |
| Total |
38,061 |
100.0 |
10 |
100.0 |
50 |
100.0 |
30 |
100.0 |
90 |
100.0 |
| Case Mothers |
| 1980-1989 |
|
| FA |
7,107 |
48.9 |
2 |
100.0 |
13 |
44.8 |
8 |
25.8 |
23 |
37.1 |
| No FA |
7,439 |
51.1 |
0 |
0.0 |
16 |
55.2 |
23 |
74.2 |
39 |
62.9 |
| Subtotal |
14,546 |
100.0 |
2 |
100.0 |
29 |
100.0 |
31 |
100.0 |
62 |
100.0 |
| 1990-1996 |
|
| FA |
4,138 |
50.5 |
1 |
16.7 |
4 |
26.7 |
6 |
50.0 |
11 |
33.3 |
| No FA |
4,064 |
49.5 |
5 |
83.3 |
11 |
73.3 |
6 |
50.0 |
22 |
66.7 |
| Subtotal |
8,202 |
100.0 |
6 |
100.0 |
15 |
100.0 |
12 |
100.0 |
33 |
100.0 |
| 1980-1996 |
|
| FA |
11,245 |
49.4 |
3 |
37.5 |
17 |
38.6 |
14 |
32.6 |
34 |
35.8 |
| No FA |
11,503 |
51.6 |
5 |
62.5 |
27 |
61.4 |
29 |
67.4 |
61 |
64.2 |
| Total |
22,748 |
100.0 |
8 |
100.0 |
44 |
100.0 |
43 |
100.0 |
95 |
100.0 |