Nocturnal Blood Pressure Decrease in Hypertensive Patients and Normotensives- Association with Obstructive Sleep Apnoea and Renal Function

Table 2: Brachial and central blood pressure from 24h ABPM in hypertensive patients and healthy controls.

	Brachial BP			CASP
	Controls (n=56)	Patients (n=75)	p Brachial	Controls (n=49)	Patients (n=64)	p CASP
24h systolic BP, mmHg	120 (8)	139 (11)	<0.0001	109 (16)**	124 (14)**	<0.0001
24h diastolic BP, mmHg	73 (4)	82 (6)	<0.0001
24h heart rate, beat/min	67 (9)	69 (10)	0.19
Daytime systolic BP, mmHg	124 (9)	141 (11)	<0.0001	113 (15)**	127 (15)**	<0.0001
Daytime diastolic BP, mmHg	75 (5)	84 (7)	<0.0001
Night-time systolic BP, mmHg	103 (8)	123 (15)	<0.0001	102 (15)	117 (15) *	<0.0001
Night-time diastolic BP, mmHg	63 (5)	73 (9)	<0.0001
Relative nocturnal SBP decrease, %	17 (7)	13 (7)	0.002	10 (5) **	7 (6) **	0.019
Absolute nocturnal SBP decrease, mmHg	21 (9)	18 (10)	0.09	11(6)**	10 (8)**	0.24
Non-dippers, % (n) ^a	18 (10)	32 (24)	0.07	50 (26)*	69 (46)**	0.032

Abbreviations: ABPM: Ambulatory Blood Pressure Monitoring, BP: Blood Pressure, CASP: Central Aortic Systolic Pressure, SBP: Systolic Blood Pressure. Data are presented as mean (SD) unless otherwise stated. ^a Percentage (number) of subjects with nocturnal systolic BP decrease < 10% of daytime. * Compared to brachial BP within the same group, p < 0.05. ** Compared to brachial BP within the same group, p <0.0001. Statistics were performed using unpaired t-test or chi-square test between groups, and paired t-test or McNemars test within groups.