Table 1: Epidemiological manifestations, clinical signs and symptoms, laboratory and imaging examinations, echocardiographic and microbiological data of infective endocarditis in four intravenous drug users.

Epidemiological, Clinical, Laboratory, Radiological Data Case 1 Case 2 Case 3 Case 4
Patient´s Age 33 years old 24 years old 30 years old 29 years old
Gender Male Male Male Male
Duration and Kind of Drug Consumption 11 years /Heroine 5 years/Heroine 9 years/Heroine 7 years/Heroine
Duration of Symptoms 5 days 18 days 23 days 6 days
Symptoms cough, chest pain, fatigue, fever, myalgia, arthralgia. cough, chest pain, dyspnea, fever, myalgia, arthralgia,. cough, chest pain, fatigue, high fever, myalgia, arthralgia high fever, myalgia, arthralgia, fatigue
Etiological Agent Staph. aureus Staph. Aureus Staph. aureus Staph. Aureus, Acinetobacilis baumani,
HIV negative Negative Negative Negative
Valve and Type of Valve Involved, Number and Size Vegetations. Tricuspid, native, 1 vegetation, 2.7cm2 Tricuspid, native, 1 vegetation, 2.87cm2 Tricuspid, native, multiple, 2-2.5 cm2 Tricuspid, native, 1 vegetation, 0.4 cm2
Vascular Phenomena Septic pulmonary emboli Septic pulmonary emboli Septic pulmonary emboli, cutaneous vasculitis
Events Observed Staphylococcic pneumonia, acute renal and hepatic failure,
conjunctival hemorrhage
Staphylococcic pneumonia, Popliteal-femoral venous thrombosis Staphylococcic pneumonia, acute cardiac, renal and hepatic failure, cutaneous vasculitis Popliteal-femoral venous thrombosis
Comorbidity No Hepatitis C Hepatitis B, Hepatitis C Hepatitis C
Surgery No Yes No No
Death No No No No
Duration of Hosp. 54 days 43 days 63 days 23 days
Treatment Vancomycin2g/day, Gentamycin 1 mg/kg every eight hours, Cefepime4g/day; Vancomycin 2g/day, Merepenem3g/day Vancomycin2g/day, Merepenem3g/day, Rifampicine 600mg/day; Vancomycin2g/day, Gentamycin1 mg/kg every eight hours, Ceftriaxone 2g/day