| Study Title | Year | Method | Findings |
|---|---|---|---|
| [9] Routine Replacement or Clinically Indicated Replacement of Peripheral Intravenous Catheters | 2018 | Randomized controlled trial | The outcomes of this study show that the catheters can remain on the site to 96 hours if they do not have complications after 72 hours. Therefore, patients experience less pain and nurses' time and equipment will be saved. |
| [10] Development of Evidence-based Nursing Practice Guidelines for Peripheral Intravenous Catheter Management in Hospitalized Children and Adult. | 2017 | Guideline | Peripheral Intravenous Catheter Catheters should be re-placed only in cases of complications. |
| [11] Complications related to the use of peripheral venous catheters: A randomized clinical trial | 2016 | Randomized controlled trial | The catheter in the experimental group was inserted without complications for an average of 3.73 (±2.25) and a maximum of 10 days while the catheter of the control group was preserved for 3.28 (± 1.66) and a maximum of seven days. |
| [12] Clinically-indicated replacement versus routine replacement of peripheral venous catheters | 2015 | Systematic Review | The review found no evidence to support changing catheters every 72 to 96 hours. Consequently, healthcare organisations may consider changing to a policy whereby catheters are changed only if clinically indicated. This would provide significant cost savings and would spare patients the unnecessary pain of routine re-sites in the absence of clinical indications. To minimise peripheral catheter-related complications, the insertion site should be inspected at each shift change and the catheter removed if signs of inflammation, infiltration, or blockage are present. |
| [16] Cost-Effectiveness Analysis of Clinically Indicated versus Routine Replacement of Peripheral Intravenous Catheters | 2014 | Randomized controlled trial | The clinically indicated catheter replacement strategy is cost saving compared with routine replacement. It is recommended that healthcare organisations consider changing to a policy whereby catheters are changed only if clinically indicated. |
| [13] Optimal timing for peripheral IV replacement | 2013 | Equivalence trial | It is hospital policy to replace the catheter every 96 hours. |
| [19] Routine versus clinically indicated replacement of peripheral intravenous catheters: a randomised controlled equivalence trial | 2012 | Multicenter, randomised, non-blinded equivalence trial | Peripheral intravenous catheters can be removed as clinically indicated; this policy will avoid millions of catheter insertions, associated discomfort, and substantial costs in both equipment and staff workload. |
| [14] Guidelines for the prevention of intravascular catheter-related infections. | 2011 | Guidelines | It is not necessary to replace peripheral IV catheters in adults more than every 72 to 96 hours. |
| [15] Clinically-indicated replacement versus routine replacement of peripheral venous catheters | 2010 | Systematic Review | The review found no conclusive evidence of benefit in changing catheters every 72 to 96 hours. Consequently, healthcare organisations may consider changing to a policy whereby catheters are changed only if clinically indicated. This would provide significant cost savings and would also be welcomed by patients, who would be spared the unnecessary pain of routine re-sites in the absence of clinical indications. |
| [17] Routine Replacement versus Clinical Monitoring of Peripheral Intravenous Catheters in a Regional Hospital in the Home Program A Randomized Controlled Trial. | 2009 | Randomized controlled trial | This randomised, controlled trial involving 316 patients in the home setting found no difference in the rate of phlebitis and/or occlusion among patients for whom a peripheral intravenous catheter was routinely re-sited at 72-96 hours and those for whom it was replaced only on clinical indication. |
| [18] Routine care of peripheral intravenous catheters versus clinically indicated replacement: randomised controlled trial | 2008 | Randomized controlled trial | Replacing peripheral intravenous catheters when clinically indicated has no effect on the incidence of failure, based on a composite measure of phlebitis or infiltration. |
| [20] Intravenous peripheral catheter dwell times: randomised controlled trial of hospital in-patients. | 2005 | Randomized controlled trial | Re-siting peripheral venous cannulas when clinically indicated compared with changing them routinely every three days does not lead to more complications and reduces costs. |
| [21] Optimal Frequency of Changing Intravenous Administration Sets: Is It Safe to Prolong Use Beyond 72 Hours? | 2001 | A prospective, nonrandomized study | In patients at low risk for infection from infusion- or catheter-related infection who are not receiving total parenteral nutrition, blood transfusions, or interleukin-2, delaying the replacement of IV tubing up to 7 days may be safe, as well as cost-effective. |
| [22] Safety of prolonging peripheral cannula and IV tubing use from 72 hours to 96 hours. | 1998 | A prospective, nonrandomized study | Phlebitis rate for our peripheral intravenous catheters at 96 hours was not significantly different from that at 72 hours. If intravenous cannulas and lines were prolonged to 96 hours, a potential cost saving of $61,200 per year could be realised. |