Table 1: Association between resistance genes to β-lactams, geographical areas of occurrence and clinical isolates in the European continent.

Europe
Country Genes
(N. reports)*
Isolated
(N. reports)*
References
France blaCTX-M-15 (2) Rectal swab (2)
Catheter
Urine
Wound exudate
Respiratory tract
(Baraniak et al. 2013)38
blaCTX-M-1
blaCTX-M-40
blaSHV-5
blaSHV-12
blaSHV-2
blaTEM-3
blaCMY-2
blaOXA-48
Italy blaCTX-M-2 Rectal swab (Baraniak et al. 2013)38
blaCTX-M-15
blaTEM-3
blaCTX-M-1
blaSHV-5
Spain blaCTX-M-1 Bloodstream
Bronchial aspirates
Clinical isolates
Non-surgical wound
Rectal swabs (2)
Sputum
Surgical wound
Urine
Vascular catheters
(Hernández et al. 2005)39
(Baraniak et al. 2013)38
(Brañas et al. 2015)40
blaCTX-M-3
blaCTX-M-9
blaCTX-M-10
blaCTX-M-15(2)
blaSHV-2 (2)
blaSHV-2a
blaSHV-5
blaSHV-12
blaDHA-1
blaTEM-3
blaTEM-4
blaTEM-25
blaTEM-133
blaOXA-48
blaVIM-1
Greece blaKPC-2 (2) Respiratory tract
Catheter tip surgical
site
Bloodstream (2)
Feces
Bronchial secretions
Pus
Central venous catheter
(Maltezou et al. 2009)41
(Souli et al. 2010)42
United
Kingdom
blaNDM
blaNDM-1
Urine (2)
Respiratory tract
(Giske et al. 2012)43
(Jain et al. 2014)44
Portugal blaCTX-M-15
blaSHV-12
blaSHV-106
blaSHV-28
blaSHV-55
blaSHV-2
blaSHV-5
Urine
Bloodstream
Exudate
Sputum
(Rodrigues et al. 2014)45
Sweden blaKPC
blaNDM-1
Urine
Respiratory tract
(Giske et al. 2012)43

1*Number of times the gene was identified.