PTS | AGE (at HU Addition) | Ph+ Cells at HU Addition | Mutational Status | Response | Time to Response (Months) | Time to Relapse (Months) | Follow-Up |
---|---|---|---|---|---|---|---|
1 | 35.9 | 100% | NA | CCR | 32 | 4 | Alive (Nilotinib→CCR) |
2 | 66.6 | 100% | NA | Res | / | / | BC after 16 mos→died |
3 | 52.0 | 100% | M244V | Res | / | / | Alive (Nilotinib→CCR) |
4 | 57.4 | 100% | NA | Res | / | / | Alive in CP |
5 | 29.9 | 95% | NA | CCR | 3 | 4 | BC after 2 mos→died |
6 | 48.4 | 100% | F317L | CCR | 12 | 12 | Alive in CP |
7 | 52.9 | 100% | L387F | Res | / | / | Alive in CP |
8 | 54.1 | 80% | NA | MCR | 7 | 4 | Alive (Nilotinib→CCR) |
9 | 57.4 | 66% | Unmutated | Res | / | / | Alive (Nilotinib→CCR) |
10 | 41.1 | 100% | NA | MCR | 3 | 10 | Alive after BMT |
11 | 67.9 | 75% | Unmutated | CCR | 7 | / | Alive in CMolR +23 mos |