Table 3: The JNK II Inhibitor Reverts the Resiquimod-Driven Increase in BAFF and APRIL Expression by CLL Cells

D-Value (K-S Analysis)
Patient Control Rq Rq + JNK Inh II
BAFF 1 22 53 29
2 18 49 23
APRIL 1 17 57 22
2 15 54 19

Leukemia cells from two CLL patient were incubated or not in the presence of Resiquimod (Rq) 1 µM, together or not with JNK Inh II (50 µg/ml). After 48 h incubation, the expression of BAFF and APRIL was determined by flow cytometry as described previously in the legend of Fig. (3). D values were estimated by Kolmogorov-Smirnov analysis as before.