Table 1: Patients’ Characteristics at Diagnosis

UPN Age Sex Treatment Status Clinical Features Sample Analyzed * Phenotype Cytogenetic Karyotype Pathologic Features
1 80 F newly diagnosed thyroid, stomach stomach CD10+, Igκ+, bcl-2-, p53+ normal GCB
2 56 M newly diagnosed stomach stomach CD10+, Igκ+, bcl-2-, bcl-6+
MUM1-, p53+		 45, XY, t(11,17)(q13, q21), +12 GCB
3 70 F newly diagnosed lymphadenopathy, stomach stomach CD10-, Ig- NA Non-GCB
4 67 F newly diagnosed mediastenal, stomach stomach CD10-, Igκ+, bcl-2+, p53± NA Non-GCB, with MALT
5 62 M newly diagnosed lymphadenopathy, stomach, testis lymph node CD10+, Igλ+ NA GCB, with MALT
6 63 M newly diagnosed lymphadenopathy, stomach lymph node CD10-, Igκ+, bcl-2+, p53- normal Non-GCB
7 69 M refractory lymphadenopathy lymph node CD10-, Igκ+ NA Non-GCB
8 48 M newly diagnosed lymphadenopathy lymph node CD10-, Igλ+, bcl-2+, p53+ NA Non-GCB
9 46 F newly diagnosed breast, bone marrow breast CD10-, Igκ+, bcl-2+, bcl-6+, MUM1-, p53± complex** GCB
10 40 F newly diagnosed breast breast CD10+, Igκ+, bcl-2-, p53+ NA GCB

Abbreviations: Upn, unique patient number; NA, not available; GCB, germinal center B-cell-like.
* CD5 negative, CD19 positive, CD20 positive and CD23 negative in all cases.
** 94xx, (add(x)(p11)ˣ2, del(2)(q13q23?)ˣ2, del(2)(q24)ˣ2, add(3)(q21)ˣ2, add(3)(q11), -5, -6, del(6)(p11), add(8)(q22)ˣ2, -9, -10, del(12)(q11q15)ˣ2, -16, -17, (del(18)(q21)?ˣ2, - 19, -19, -21, -22, +10mar