Malignant T Cells Exhibit CD45 Resistant Stat3 Activation and Proliferation in Cutaneous T-Cell Lymphoma

Fig. (4) CTCL cells exhibit increased resistance to Galectin-1 mediated inhibition of proliferation. Jurkat T cells or malignant T cells from CTCL (MyLa2000) were incubated for 48 hours with 3.5 µM of Galectin-1. [³H]thymidine was added 24 hours before harvest and the incorporation measured in a scintillation counter. The results are expressed as mean counts per minute (cpm) from triplicate cultures.