Table 6:
In vitro
Inhibitory activity (%) on MAO-A and on MAO-B (%).
Compounds
MAO-A (%) @ 10μΜ
MAO-B (%) @ 10μΜ or IC
50
μΜ
4b
no
24
4f
no
no
4i
25
no
11b
15
IC
50
= 9.5 μΜ
11e
no
9
11f
16
8
13a
47
33
13b
12
no
13e
18
15
13i
6
9
Clorgyline
IC
50
= 2.4 nM
IC
50
= 2.4 μΜ
No: no activity under the reported conditions