Fig. (2) Mitochondrial membrane permeabilization. Results present permeabilization of cells exposed to NBQ-48 and ABQ-48. A 51.3% of Cells treated with NBQ-48 presented permeabilized membrane versus 57.67% of ABQ-48 treated cells presented mitochondrial membrane permeabilization. Positive controls Camptothecin and Valinomycin presented 51.6% and 55.3% respectively. Clear and significant statistical difference was observed on mitochondrial membrane permeabilization among the tested compounds and the negative control (P<0.05).