Table 4: QSAR parameters: cLogP, molecular weight (MW), number of H bond donors and H bond acceptors value for compounds 4(a-o).

Compounds cLogP Donor Acceptor Lipinski violations Mol. wt
4a 3.43 0 4 0 315.36
4b 4.14 0 4 0 349.81
4c 4.74 0 4 0 384.25
4d 4.86 0 4 0 384.25
4e 4.86 0 4 0 384.25
4f 3.93 0 4 0 329.39
4g 3.35 0 5 0 345.39
4h 3.35 0 5 0 345.39
4i 3.44 0 6 0 375.42
4j 3.09 0 6 0 375.42
4k 3.57 0 4 0 333.35
4l 4.86 0 4 0 357.44
4m 4.30 0 4 0 394.26
4n 5.53 0 5 1 407.46
4o 2.61 0 5 0 305.33

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