Table 4: QSAR parameters: cLogP, molecular weight (MW), number of H bond donors and H bond acceptors value for compounds 4(a-o).
| Compounds |
cLogP |
Donor |
Acceptor |
Lipinski violations |
Mol. wt |
| 4a |
3.43 |
0 |
4 |
0 |
315.36 |
| 4b |
4.14 |
0 |
4 |
0 |
349.81 |
| 4c |
4.74 |
0 |
4 |
0 |
384.25 |
| 4d |
4.86 |
0 |
4 |
0 |
384.25 |
| 4e |
4.86 |
0 |
4 |
0 |
384.25 |
| 4f |
3.93 |
0 |
4 |
0 |
329.39 |
| 4g |
3.35 |
0 |
5 |
0 |
345.39 |
| 4h |
3.35 |
0 |
5 |
0 |
345.39 |
| 4i |
3.44 |
0 |
6 |
0 |
375.42 |
| 4j |
3.09 |
0 |
6 |
0 |
375.42 |
| 4k |
3.57 |
0 |
4 |
0 |
333.35 |
| 4l |
4.86 |
0 |
4 |
0 |
357.44 |
| 4m |
4.30 |
0 |
4 |
0 |
394.26 |
| 4n |
5.53 |
0 |
5 |
1 |
407.46 |
| 4o |
2.61 |
0 |
5 |
0 |
305.33 |