Table 5: Screening data for compounds 34-47.

Cmpd	R, R1, R2 & R3	CC50 (µM)
		HT29	PC3	MDA-MB-231
34	R1 & R3 = H, R2 = SCH3, R = methyl	7.43±0.48	20.18±3.20	9.06±2.26
35	R1 & R3 = H, R2 = SCH3, R = ethyl	8.33±1.64	22.59±3.25	11.87±2.61
36	R1 & R3 = H, R2 = SCH3, R = phenyl	9.94±0.83	39.58±14.8	17.72±2.10
37	R1 & R3 = H, R2 = SCH3, R = p-tolyl	8.08±0.60	>50.00	20.53±5.18
38	R1 & R3 = H, R2 = SCH3, R = 1-naphthyl	17.03±3.73	>50.00	38.90±10.32
39	R1 & R3 = H, R2 = SCH3, R = 2-naphthyl	25.64±5.91	>50.00	12.92±2.39
40	R1 & R3 = H, R2 = SCH3, R = 5-N,N-Dimethylamino-1-naphthyl	38.41±10.12	>50.00	>50.00
41	R1, R2 & R3 = OCH3, R = methyl	20.02±4.86	18.85±2.47	12.91±1.79
42	R1, R2 & R3 = OCH3, R = ethyl	15.56±5.56	15.13±1.84	6.58±1.39
43	R1, R2 & R3 = OCH3, R = phenyl	43.77±23.02	40.88±16.80	16.28±3.96
44	R1, R2 & R3 = OCH3, R = p-tolyl	>50.00	>50.00	44.48±25.65
45	R1, R2 & R3 = OCH3, R = 1-naphthyl	>50.00	>50.00	>50.00
46	R1, R2 & R3 = OCH3, R = 2-naphthyl	>50.00	>50.00	>50.00
47	R1, R2 & R3 = OCH3, R = 5-N,N-Dimethylamino-1-naphthyl	>50.00	>50.00	>50.00