Table 1: Colon targeting sites, diseases and drugs for their therapy.

Type of Action Disease Conditions Drug for Therapy
Topical Action Inflammatory Bowel Diseases, Irritable bowel disease and Crohn’s disease. Chronic Pancreatitis. Hydrocortisone, Budenoside, Prednisolone, Sulphasalazine, Olsalazine, Mesalazine, Balsalazide.
Local Action Pancreatactomy and cystic fibrosis, Colorectal cancer Digestive enzyme supplements,
5-Flourouracil
Systemic Action To prevent gastric irritation
To prevent first pass metabolism of orally ingested drugs
Oral delivery of peptides
Oral delivery of vaccines
NSAIDS
Steroids
Insulin
Typhoid