Fig. (1) Albumin structure; Crystallographic studies stated that albumin HSA a heart-shaped tertiary structure with high α-helical content and 3 homologous domains, each comprised of 2 subdomains. The Cys34 (ORANGE) provides thiol properties conferring antioxidant ability to the protein. From the reduced form (mercaptoalbumin), albumin can be oxidized up to a highly oxidized state (sulfenic/sulfonic acid, known as nonmercaptoalbumin 2) The N-terminal (BLUE) acts as scavenge of free metals usually involved in pro-oxidant reactions, contributing to the antioxidant capacity of the molecule [13].