Table 1: Serum Levels of Biochemical and Inflammatory Markers for Calcitriol Therapy in Patients on HD with s-HPT.

Serum
Marker
(Unit)		 HD Patients with Calcitriol Therapy
Mean ±SD (95% CI))		 p Value
Pre-treatment
(Baseline)		 Post-treatment
8 Weeks 16 Weeks
Ca (mg/dl) 7.93 ±0.576
(7.61 - 8.253)		 8.086 ±0.488 *
(7.816 - 8.357)		 8.4 ±0.6** ##
(8.065 - 8.73)		 * 0.048
** 0.001
## 0.003
P (mg/dl) 3.64 ±0.35
(3.45 - 3.84)		 3.85 ±0.32 **
(3.67 - 4.03)		 4.1 ±0.366 ** ##
(3.89 - 4.3)		 ** 0.001
** 0.001
## 0.003
ALP (IU/L) 519.7 ±65.65
(483.37 - 556.09)		 519.46 ±60.43
(486.0 - 552.9)		 449.7 ±94.29
(477.5 - 551.94)		 >0.05
iPTH (pg/ml) 403.2 ±76.98
(360.56 - 445.8)		 373.7 ±79.64 **
(329.6 - 417.8)		 338.6 ±77.45 ** ##
(295.7 - 381.49)		 ** 0.001
** 0.001
## 0.001
CRP (mg/L) 23.17 ±8.11
(18.68 - 27.66)		 20.46 ±6.7 *
(16.729 - 24.19)		 16.11 ±7.23 ** ##
(12.105 - 20.13)		 * 0.01
** 0.001
## 0.001
IL-6 (pg/ml) 27.45 ±11.97
(20.8 - 34.08)		 25.34 ±10.279 *
(19.65 - 31.04)		 22.47 ±10.95 **#
(16.4 - 28.53)		 * 0.027
** 0.005
# 0.011

Data: Expressed as mean ±SD (95%CI of mean)Markers:Ca: Calcium,P: phosphorus, ALP : Alkaline Phosphatase,iPTH: Intact Parathyroid Hormone, CRP: C Reactive Protein, IL-6: Interleukin 6The comparison between means was assessed using Wilcoxon Signed Rank test at 16 weeks post treatment was considered significant at p Value: * <0.05 & ** <0.005 compared to pre-treatment and #<0.05 &##<0.005 compared to 8 weeks post-treatment. Serum level of CRP was reduced by 11.7% at 8 weeks and 30.5% at 16 weeks of treatment Serum level of IL-6 was reduced by 7.68% at 8 weeks and 18.14% at 16 weeks of treatment