Table 5: Discriminative Power (DP) of the 50 decoys generated by the different scoring functions and rescored by each another on all the 33 DNA-ligand complexes, minor groove only and intercalated only complexes.

Scoring Functions Rescoring Functions
Autodock ASP ChemScore GoldScore
All decoys
ASP -0.01 -0.01 -0.11 -0.20
ChemScore -0.07 -0.33 -0.01 -0.21
GoldScore -0.02 -0.28 -0.28 -0.03
Autodock -0.46 -0.26 -0.65 -0.22
Minor groove decoys
ASP -0.03 -0.03 -0.20 -0.20
ChemScore -0.13 -0.17 -0.03 -0.20
GoldScore -0.04 -0.09 -0.14 -0.05
Autodock -0.55 -0.37 -0.73 -0.41
Intercalated decoys
ASP 0.00 -0.13 -0.05 -0.10
ChemScore -0.01 -0.50 0.00 -0.30
GoldScore -0.01 -0.25 -0.53 -0.01
Autodock -0.05 -0.13 -0.68 -0.11

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