Scheme 2
Synthetic routes for synthesis of derivatives
5c
-
7c
,
8a
,
b
,
c
-
15a
,
b
,
c
,
16c
-
26c
. i: 100°C, 6h-120h; ii: DMA, 100°C, 24h-168h; iii: toluene, 100°C, 3.5h-96h; iv: DMF, 80°C, 2-48h (
8a
,
b
-
15a
,
b
); DMA, 100°C, 72-192h (
8c
-
15c
).