Table 1: The chemical structure, lipophilicity (log P), total polar surface area and molecular mass of compounds are given in this paper. Calculations were done using the Pallas 3.8 program of CompuDrug/ ComInnex Inc. (Budapest, Hungary)
Compound |
Chemical Structure |
logP |
TPSA (Å2) |
MWcation |
Ref. |
K-347 |
|
-1.89 |
36.47 |
213.28 |
[14] |
K-027 |
|
-7.82 |
85.47 |
286.37 |
[15] |
K-048 |
|
-7.63 |
83.47 |
300.40 |
[16] |
K-117 |
|
-7.77 |
82.17 |
316.40 |
[17] |
K-127 |
|
-8.47 |
92.67 |
316.40 |
[17] |
K-203 |
|
-7.88 |
83.44 |
298.38 |
[18] |
K-269 |
|
-3.47 |
104.31 |
329.42 |
[14] |
K-456 |
|
-7.82 |
83.44 |
286.37 |
[14] |
K-867 |
|
-6.78 |
83.44 |
332.82 |
[15] |
K-868 |
|
-7.23 |
83.44 |
355.25 |
[15] |
K-870 |
|
-6.58 |
83.44 |
367.26 |
[15] |
Metoxime |
|
-7.10 |
72.94 |
258.31 |
[9] |
Obidoxime |
|
-7,15 |
82,17 |
288.34 |
[9] |
Pralidoxime |
|
-3,36 |
36.47 |
137.18 |
[3] |