Fig. (3) Concentration dependence of telomerase inhibition by NSC 35489.A. Inhibition of telomerase by NSC 35489. Lanes 1-3, 5 nM; lanes 4-6, 50 nM; lanes 7-9, 500 nM; lanes 10-12, 5 μM; and lanes 13-15, 50 μM. The lane marked – is a control for telomerase activity in the presence of a known telomerase inhibitor: hTR-AS at 200nM. LC is a loading control as in Figure 2. B. Dose response curve for telomerase inhibition by NSC 35489.