| Compound Designation | Inhibits HMG-CoA? | Est. IC50 | Approx. Molecular Weight | H-Donors |
|---|---|---|---|---|
| CVSlead1 | No* | -- | 450 | 3 |
| CVSlead2 | No | -- | -- | -- |
| CVSlead3 | No | -- | -- | -- |
| CVSlead4 | Insoluable under assay conditions | |||
| CVSlead5 | Yes | 510-764uM | 280 | 3 |
| CVSlead6 | Yes | 73uM | 300 | 0 |
| CVSlead7 | No | -- | -- | -- |
| CVSlead8 | Similar to CVSlead4, and presently insoluable—trials continuing | |||