Table 2.: Peptide antagonists of glucagon receptors.

  Dosage Mode of Delivery Efficacy References
Bicyclic 19-residue peptide BI-32169 320-440 nM Subcutaneous (s.c.) or intravenous (i.v.) Investigations still in the experimental phase. [42, 43]
Des-His(1)-[Glu(9)]-glucagon amide 10 µg Intravenously (i.v.) Single dose blocks up to 40-80% of endo- as well as exogenous glucagon, including free as well as hepatocyte-bound. [39,40, 43-45]

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